Report Code : BII 941 Jan-2022 Healthcare Format : PDF Pages : 216
Digital PCR is an end-point PCR method for absolute quantification and analysis of minority sequences in the presence of similar majority sequences. Digital PCR (dPCR) allows for precise and sensitive nucleic acid measurement. Because the amplified result is identified by agarose gel electrophoresis, traditional PCR is a semi-quantitative end-point analysis. Real-time PCR (or qPCR) uses fluorescence-based detection to track the amount of amplified product that has accumulated as the reaction advances.
Only relative quantification is possible with qPCR because it requires normalization to controls or a standard curve. Variations in amplification efficiency may also influence qPCR results. Droplet digital PCR, chip-based digital PCR, and beamed digital PCR are the three types of digital PCR.
Although digital PCR applications benefit the molecular biology industry, the high price associated with high-tech digital PCR devices function as a stumbling block when compared to the cost of RT-PCR. Furthermore, despite the fact that digital PCR is gaining popularity, demand for real-time PCR remains strong in applications like as genotyping and gene expression studies, owing to the lower cost of RT PCR.
Furthermore, rising competition in Next Generation Sequencing (NGS), which is used to sequence whole genomes, full exomes, transcriptomes, and specific gene sections, is a factor contributing to the decline in demand for digital PCR. Because targeted next-generation sequencing is more cost-effective, the digital polymerase chain reaction market's growth may be limited.
According to Business Intelligence Insights "Digital PCR market is expected to grow from USD 562.10 million in 2021 to USD 1063.75 million by 2028, at a CAGR of 8.30% during the forecast period 2022-2030.
In numerous sections of the healthcare business, the impact of the COVID-19 pandemic was measured. Diagnostics was the most affected industry. The COVID-19 pandemic had a positive impact on the growth of RT-PCR and digital PCR, both of which are used in diagnostics and drug discovery. The development of novel droplet digital PCR kits for the detection of COVID-19 is a major industrial priority. The diagnostics industry was the hardest hit, with a significant increase in the PCR market. As they are used for diagnostic and drug discovery, digital PCR and real-time PCR have seen a lot of interest. Industry vendors are increasingly focusing on developing droplet digital PCR kits to detect COVID-19. Regulatory agencies have expressed strong support for approving these tests in order to mitigate the effects of the COVID-19 pandemic
Drivers
Restraints
By Technology
The Droplet Digital PCR category dominated the market with more than 33% of the market share
In 2021, the market for Digital PCR was dominated by Droplet Digital PCR as a technology. Droplet digital PCR (ddPCR) is a digital PCR method that utilizes water-oil emulsion droplet technology. A sample is divided into 20,000 droplets, with each droplet undergoing PCR amplification of the template molecules. The reagents and procedures utilized in ddPCR are identical to those used in most TaqMan probe-based experiments. The ddPCR technology relies heavily on enormous sample partitioning. Apart from the ddPCR's advantages, drivers driving the segment's growth include the rising prevalence of cancer and infectious diseases, as well as increased financing and advancements in the biotechnology sector.
By Application
The Research category dominated the market with more than 35% of the market share
The mode of application in which Digital PCR can be taken is Clinical Diagnostics, Forensic And Others, and Research. In the worldwide Digital PCR industry, Research is the most popular application mode. qPCR analysis is a commonly used approach in research, particularly in gene-based research to find gene aberrations and mutations, identify specific genetic markers in oncology and genomic investigations, and drug screening and lead identification in drug discovery. The growing trend of qPCR-based research data publication, expanding qPCR-based genomic investigations, and the continuing trend of laboratory automation and robotics integration with qPCR processes all promote this market segment's growth.
By Technology
By Product Type
By Application
By End User
By Region
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North America dominated the market with more than 30% of the market share
The presence of important companies, the high frequency of chronic diseases in the region, and the developed healthcare infrastructure are all contributing to market expansion. Furthermore, favorable government efforts and an increase in the number of research partnerships are projected to propel the industry forward. Due to favorable healthcare legislation, a large number of patients, and a developed healthcare market, the United States has the largest share in this region.
Report Attributes |
Details |
---|---|
Market Size Value in 2021 | USD 562.10 million |
Market Size Value in 2030 | USD 1063.75 million |
Growth Rate | 8.30% |
Base Year | 2021 |
Forecast Period | 2022-2030 |
Historical Data | 2018-2020 |
Forecast Units | (USD million) |
Countries Covered | North America: U.S and Canada Europe: Germany, France, Italy, U.K, Spain, Russia, Rest of Europe APAC: China, Japan, South Korea, India, Australia, South East Asia, Rest of Asia Pacific Latin America: Brazil, Mexico Middle East And Africa: Saudi Arab, South Africa, UAE |
Segments Covered | By Technology ,By Product Type, By Application , By End User , By Region |
Competitive landscape | Leading companies, Competitive strategies and Consumer engagement scope |
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